TOV-21G人卵巢癌細胞

CRL-11730 TOV-21G 人卵巢癌細胞

TOV-21G (ATCC® CRL-11730™)

Organism Homo sapiens, human

Tissue

ovary

Product Format frozen

Morphology epithelial

Culture Properties adherent

Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Disease grade 3, stage III,primary malignant adenocarcinoma; clear cell carcinoma

Age 62 years

Gender female

Storage Conditions liquid nitrogen vapor phase

Karyotype  47, XX, +10 Ref

Derivation

This cell line was initiated in October of 1991 from a patient of French-Canadian descent with no family history of ovarian cancer.

Clinical Data

female

Oncogene  p53 + (wild type)

Genes Expressed

keratin

Cellular Products

keratin

Tumorigenic  Yes

Effects

Yes, form colonies in soft agar

Yes, the cells are tumorigenic in nude mice

Comments

Like OV-90 (ATCC CRL-11732), the OV-21G (ATCC CRL-11730) cell line exhibits a deletion at chromosome 3p24. The TOV-112D (ATCC CRL-11731) cell line does not exhibit a deletion at chromosome 3p24.