美國Primary Rat Podocyte大鼠原代腎足細胞是美國PrimCells原代細胞:PrimCells的原代細胞產品采用*的高效提取方法, 分離,并通過盡量縮短體外培養時間從而保證其更接近體原始狀態,以適應客戶對細胞品質的嚴格要求。PrimCells亦是多種腎臟來源原代細胞的世界獨JIA供應商,為多家藥物研發企業提供藥物藥效與毒理測試。此外,PrimCells還開發出多種轉基因胚胎干細胞、原代胚胎成纖維細胞等產品,是干細胞與重編程領域的報告基因原代細胞提供商。
Species:
Sprague Dawley
Catalog Number:
PCKDR01
Cell Number:
~1x106
Storage/Shipping:
Freshly Isolated
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from Sprague Dawley rats to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.